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Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

Alliance of Genome Resources2026-08-01 收录

线粒体功能障碍转录组

辅酶Q缺乏症研究

数据链接：

http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=GSE96518 数据链接链接失效反馈

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资源简介：

Differential gene expression in mouse models of mitochondrial dysfunction various mutants vs. wild type

应用场景：

线粒体功能障碍转录组

ER应激信号调控

Mitochondrial dysfunction causes biophysical, metabolic and signalling changes that alter homeostasis and reprogram cells. We used a Drosophila model in which TFAM is overexpressed in the nervous syst

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Expression data from 2 wildtype and 8 C. elegans ETC mutants

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线虫代谢

Utilizing C. elegans as a model of mitochondrial dysfunction provides insight into cellular adaptations which occur as a consequence of genetic alterations causative of human disease. We characterize

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EPAS1 directs a network of genes implicated in mitochondrial dysfunction in arrhythmogenic cardiomyopathy [RNA-seq]

心肌病分子病理学

线粒体功能障碍转录组

Patients diagnosed with arrhythmogenic cardiomyopathy (ACM) often harbor desmosomal mutations, predisposing them to arrhythmia and sudden cardiac death. The molecular mechanisms underlying pathobiolog

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RNA-seq of wild-type and Cox10-/- muscle stem cells (mouse)

干细胞生物学

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We report the transcriptome changes in purified mouse muscle stem cells in response to deletion of the Cox10 gene. This study identifies changes in the muscle stem cell population in response to mito

NIAID Data Ecosystem20

Genome-wide Responses to Mitochondrial Dysfunction

线粒体功能障碍转录组

酵母信号传导

Mitochondrial dysfunction can lead to diverse cellular and organismal responses. We used DNA microarrays to characterize the transcriptional responses to different mitochondrial perturbations in Sacch

PubMed Central00

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

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