Diastereoselective Synthesis of γ-Lactams by a One-Pot, Four-Component Reaction
收藏NIAID Data Ecosystem2026-03-06 收录
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A new one-pot, four-component reaction (4CR) between amines, maleic anhydrides, aldehydes, and thiols has been discovered to form tetra- and pentasubstituted γ-lactams with high diastereoselectivity. Each component is independently variable and employed in equivalent stoichiometry, producing only water as a byproduct.
创建时间：
2016-06-03
