Combinatorial Nicking Mutagenesis

NIAID Data Ecosystem2026-03-12 收录

抗体工程

组合诱变文库

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA744264 数据链接链接失效反馈

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资源简介：

Near comprehensive combinatorial libraries for anti-influenza antibody scFv's made in E.coli

创建时间：

2021-07-06

In silico site-directed mutagenesis of neutralizing mAb 4C4 and analysis of its interaction with G-H loop of VP1 to explore its therapeutic applications against FMD

抗体工程

病毒治疗

Investigating the behaviour of bio-molecules through computational mutagenesis is gaining interest to facilitate the development of new therapeutic solutions for infectious diseases. The antigenetical

DataCite Commons2020-08-28 更新340

Spatial proteomics reveals differences in the cellular architecture of antibody-producing CHO and plasma-cell derived cells

空间蛋白质组学

抗体工程

Most of the recombinant biotherapeutics employed today to combat severe illnesses e.g. various types of cancer or autoimmune diseases are produced by Chinese hamster ovary (CHO) cells. To meet the gro

NIAID Data Ecosystem50

CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain

结构生物学

抗体工程

CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain Descriptor: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ... Authors:

Protein Data Bank Japan2024-10-16 更新40

HCAb

抗体工程

新冠病毒

Raw dataf for manuscript with the title of " Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants ".

DataCite Commons2023-02-03 更新120

ADAPT consensus Z-scores used in VHH-72 mutation selection.

抗体工程

突变体筛选

ADAPT consensus Z-scores used in VHH-72 mutation selection.

NIAID Data Ecosystem50