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Transcription profiling of BMM and GM-BMM from wild type and IFNAR1 -/- mice

ChEBI2008-10-15 更新2026-07-21 收录

免疫细胞转录组

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-1827 数据链接链接失效反馈

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Transcription profiling of BMM and GM-BMM from wild type and IFNAR1 -/- mice

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创建时间：

2008-10-15

细胞分化调控

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To analyze the effect of type I IFN on global gene expression in differentiating monocytes, we employed microarray-based gene expression profiling. The MACS-purified mouse BM monocytes were cultured i

NIAID Data Ecosystem90

High dose IFN-𝛽 activates GAF to enhance expression of ISGF3 target genes in epithelial cells

干扰素信号通路

基因表达调控

GAF is transcriptionally inactive in epithelial cells but enhances expression of ISGF3 target genes, thus functioning as a dose-sensitive amplifier of the IFN-𝛽 response. Sequencing data from MLE-12

NIAID Data Ecosystem50

MDA5-binding interferon-inducible RNA sequencing

MDA5-RNA相互作用鉴定

干扰素信号通路

The goal is to assess whether interferon-inducible RNA regulates type I IFN through cytosolic RNA sensor MDA5. Huh7 cells were treated with or without IFN beta. Anti-MDA5 immunoprecipitation was condu

NIAID Data Ecosystem50

IFNb induced genes in MEFs

干扰素信号通路

病毒基因表达

A number of IFN-induced proteins are believed to be responsible for the antiviral state induced by IFNs. Our microarray analysis of IFN-regulated genes in MEFs from wild-type mice identified 124 probe

NIAID Data Ecosystem60

Transcriptome analysis of innate intestinal intraepithelial lymphocytes. Mus musculus

肠道上皮内淋巴细胞

免疫细胞转录组

Characterization of intraepithelial ILC on the basis of CD8α and Ly49E expression Overall design: CD3- CD45+ CD8αα- Ly49E+, CD3- CD45+ CD8αα+ Ly49E+ and CD3- CD45+ CD8αα+ Ly49E- cells were sorted to h

NIAID Data Ecosystem50

Transcription profiling of BMM and GM-BMM from wild type and IFNAR1 -/- mice

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