Co-crystal Structure of human SMYD3 with Isoxazole Amides Inhibitors
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Co-crystal Structure of human SMYD3 with Isoxazole Amides Inhibitors Descriptor: 5-cyclopropyl-N-[1-(methylsulfonyl)piperidin-4-yl]-1,2-oxazole-3-carboxamide, Histone-lysine N-methyltransferase SMYD3, MAGNESIUM ION, ... Authors: Elkins, P.A, Bonnette, W.G. Deposit date: 2019-06-06 Release date: 2020-01-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors. Acs Med.Chem.Lett., 11, 2020
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2019-06-06
