Characterization Type II-C CRISPR Cas systems from Defluviimonas sp. 20V17 and Pasteurella pneumotropica. Illumina sequencing reads from PpCas9 specificity tests.

NIAID Data Ecosystem70

Study on genome editing tool

体内基因编辑

基因工程工具开发

To develop a genome tool with high efficiency in in vivo study

NIAID Data Ecosystem40

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

CRISPR-Cas3结构机制

基因工程工具开发

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: AcrIC9, Cas11, Cas5, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22

Protein Data Bank Japan2025-05-21 更新80

Engineering a transposon-associated TnpB-omegaRNA system for efficient gene editing and phenotypic correction of a tyrosinaemia mouse model

基因工程工具开发

疾病模型研究

Transposon-associated ribonucleoprotein TnpB is known to be the ancestry endonuclease of diverse Cas12 effector proteins from type-V CRISPR system. Given its small size (409 aa), it is of interest to

NIAID Data Ecosystem50

Engineered APOBEC3A deaminase for highly accurate cytosine base editing.

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