Identification of proteins in the plasma associated with heifer infertility

We carried out an experiment to test the hypothesis that differences in protein abundance due to fertility fitness would be shared between heifers of different breeds. We produced proteome data from the plasma collected from 22 heifers (purebred Angus heifers (n=12), purebred Holstein (n=10) heifers). The protein Alpha-ketoglutarate-dependent dioxygenase FTO was more abundant in the plasma collected from Fertile heifers relative to Sub-fertile counterparts (FDR < 0.05).