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<i>Meta</i>-Selective Arene C–H Bond Olefination of Arylacetic Acid Using a Nitrile-Based Directing Group

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NIAID Data Ecosystem2026-03-09 收录
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A nitrile-based template attached with a phenylacetic acid framework promoted meta-selective C–H bond olefination. This palladium-catalyzed protocol is applicable to a wide range of substituted phenylacetic acids and tolerates a variety of functional groups. The versatility of this operationally simple method has been demonstrated through drug diversification.

创建时间:
2014-11-07
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