To develop standardized protocols for rapid delamanid susceptibility testing (DST) using the colorimetric resazurin microtiter assay (REMA) and the semi-automated BACTEC⢠MGIT⢠960 system (MGIT) b
The projects aims to find the biotargets of azolo[1,2,4,5]tetrazines within M. smegmatis, their mechanisms of action and thus to further investigate the possibility of their use in antituberculosis ch
Tuberculosis (TB) has surpassed HIV as the leading infectious disease killer worldwide since 2014. The main pathogen, Mycobacterium tuberculosis (Mtb), contains ~4,000 genes that account for ~90% of t