Identification of cellular CDK9 substrates using an analog-sensitive cell line
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介:
Analog-sensitive kinase technology allows for specific inhibition of a given kinase. Here we utilize an analog-sensitive CDK9 cell line to determine the impact of CDK9 inhibition on the phospho-proteome of human cells. Specifically, we aim to identify substrates of CDK9 in a quantitative way using stable isotope labeling by amino acids in cell culture (SILAC) followed by LC-MS/MS.
创建时间:
2019-11-11



