Contributions of the enteric nervous system and immune system to intestinal health and disease

The gut, or gastrointestinal tract, is enriched with nerve cells and immune cells, which regulate its activities and protect it from disease. These cells also interact with each other to ensure coordinated responses of the gut but the full extent of these interactions is unknown. This study delved into how gut nerves and immune cells interact and respond to changes. The results of this thesis provide novel findings related to intestinal neuroimmune interactions and gut function as determined during health, helminth infection, dietary changes or inflammation.