Structure of human PARG complexed with JA2120
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Structure of human PARG complexed with JA2120 Descriptor: 1,3-dimethyl-8-{[2-(morpholin-4-yl)ethyl]sulfanyl}-3,7-dihydro-1H-purine-2,6-dione, Poly(ADP-ribose) glycohydrolase Authors: Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. Deposit date: 2019-03-15 Release date: 2019-12-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
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2019-03-15
