Crystal structure of ERK2 with an allosteric inhibitor
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Crystal structure of ERK2 with an allosteric inhibitor Descriptor: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Yoshida, M, Kinoshita, T. Deposit date: 2021-11-30 Release date: 2022-02-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Identification of a novel target site for ATP-independent ERK2 inhibitors. Biochem.Biophys.Res.Commun., 593, 2022
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2021-11-30
