The spliceosome is an exploitable vulnerability in RB1-mutant cancer
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介:
RB transcriptional corepressor 1 (RB1) is frequently mutated in human cancers, we discover a new target of oncogenic stress in RB1-mutant cells. Overall design: RNA-seq, ChIP-seq and WES are used to profile RB1 mutant fibroblasts, RB1 mutant iPSC derived mesenchyma stem cell, osteoblast and osteosarcoma cancer cell lines.
创建时间:
2022-04-04



