We performed ChIP-seq on MV4-11 or OCI-AML3 cells which had been treated with DMSO or 5 nM of the FLT3 inhibitor Quizartinib (AC220) to determine the location of ATF4 or RNAPII across the genome. Over
We performed 3'-RNA-Sequencing on RNA isolated from human MV4-11 and OCI-AML3 cells which had been treated with DMSO or the FLT3 inhibitor Quizartinib (AC220) to perform differential gene expression a
In this study, we identify a significant induction of a CD81+ erythroblast subpopulation in the spleens of an AML mouse model, which can promote AML cell proliferation and reduce mice survival. To inv
