tdp43-lof-db/

Our interactive database (https://www.scotterlab.auckland.ac.nz/research-themes/tdp43-lof-db/) allows further exploration of TDP-43 DEG and DEU targets. Together, these data identify TDP-43 targets that can be exploited therapeutically or used to validate loss-of-function processes. This article has an associated First Person interview with the first author of the paper.本研究搭建的交互式数据库（https://www.scotterlab.auckland.ac.nz/research-themes/tdp-43-lof-db/）可用于进一步探究TAR DNA结合蛋白43（TDP-43）的差异表达基因（Differentially Expressed Genes，DEG）与差异外显子使用（Differential Exon Usage，DEU）靶标。综上，本研究数据鉴定出可用于治疗性开发或验证功能丧失过程的TDP-43靶标。本文附带一篇与第一作者的第一人称专访。

搜集汇总

背景与挑战

背景概述

该数据集是一个交互式数据库，专注于探索TDP-43的功能丧失靶点，旨在为治疗应用或验证相关生物过程提供支持。