Age Map, Hippocampus (B)

To assess the transcriptional changes in different brain regions and spinal cord associated with aging and either a caloric restricted (CR) or ad libitum (AL) diet. cDNA microarray and quantitative PCR analyses were used to examine the transcriptomes of various neuronal tissues in young, middle aged and old mice. Mice of both genders were examined as well as the effects of their placement on either caloric restricted (CR) or ad libitum (AL) diets. Keywords: age-, gender-, and diet- comparison 67 mice were compared according to age, gender, and diet本数据集旨在评估与衰老及热量限制（caloric restricted, CR）、自由采食（ad libitum, AL）饮食相关的不同脑区与脊髓的转录组变化。研究采用cDNA微阵列（cDNA microarray）与定量PCR（quantitative PCR）分析，对年轻、中年及老年小鼠的多种神经组织转录组进行检测。实验同时涵盖雌雄小鼠，探究喂食CR或AL饮食对其产生的影响。关键词：年龄、性别与饮食比较。本研究共纳入67只小鼠，按年龄、性别及饮食条件分组开展对比分析。