SRSF1 overexpression in pancreatic normal ductal and KC organoids
收藏NIAID Data Ecosystem2026-03-12 收录
官方服务:
资源简介:
SRSF1-mediated alternative splicing changes based on wild type or KrasG12D context.
应用场景:
创建时间:
2021-07-18
相关数据集
Genome wide screening for alternative splicing events in pancreatic cancer. Homo sapiens
We used Affymetrix GeneChip® Human Exon 1.0 ST Arrays to identify alternative splicing events in 15 samples of PDAC compared to 6 non-tumor samples. Several commercial and open source software approac
NIAID Data Ecosystem20
TUT1 promotes PDAC progression through Alternative Splicing [3‘-seq]. TUT1 promotes PDAC progression through Alternative Splicing [3‘-seq]
Pancreatic ductal adenocarcinoma (PDAC) is a malignant cancer with high lethality rate. In this study, we identify that terminal Uridylyl Transferase 1 (TUT1), a specific terminal uridylyltransferase
NIAID Data Ecosystem20
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer
Integrating transcriptomic analyses of both clinical PDAC and PDAC models, we identified that the most common neomorphic TP53 mutation (p53R175H) rewires RNA splicing promoting transcriptome-wide rete
NIAID Data Ecosystem00
Gene expression and alternative splicing in pancreatic ductal adenocarcinoma (PDAC) [gene level]. Homo sapiens
Alternative splicing is a key event to human transcriptome and proteome diversity and complexity. Recent evidence suggests that pancreatic cancer might possess particular patterns of splice variation
NIAID Data Ecosystem20
Expression data from human pancreatic cancer cell lines and mouse orthotopic tumors generated using human PDAC cell lines replete and depleted for RBFOX2. Expression data from human pancreatic cancer cell lines and mouse orthotopic tumors generated using human PDAC cell lines replete and depleted for RBFOX2
RBFOX2 is an RNA binding protein that directs alternative splicing. In this study, we characterized RBFOX2-mediated alternative splicing in pancreatic cancer (PDAC) In this dataset, we assayed gene-le
NIAID Data Ecosystem10



