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Rhodium-Catalyzed Asymmetric [2 + 2 + 2] Cyclization of 1,6-Enynes with Aliphatic and Aromatic Alkenes

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Figshare2017-05-22 更新2026-04-29 收录
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It has been established that a cationic rhodium­(I)/(R)-MeO-BIPHEP complex catalyzes the asymmetric [2 + 2 + 2] cyclization of 1,6-enynes with aliphatic and aromatic alkenes to produce chiral cyclic dienes through β-hydride elimination from rhodacycle intermediates. Thus, obtained chiral cyclic dienes could be converted to chiral spirocompounds without racemization.

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2017-05-22
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