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Modified Stat1 Confers Enhanced Interferon Responsiveness and Improved Baseline Antiviral Host Defense

ChEBI2015-09-01 更新2026-07-12 收录

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-61413 数据链接链接失效反馈

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Modified Stat1 Confers Enhanced Interferon Responsiveness and Improved Baseline Antiviral Host Defense

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创建时间：

2015-09-01

蛋白质互作

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Additional file 3. GO term enrichment on significantly changed SILAC ratios of IFN-stimulated cells at 4 h or 24 h IFN treatment.

DataCite Commons2020-08-25 更新60

Chromatin profiling of GM12878 cells with and without a predicted enhancer element

增强子功能验证

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We test the predicted interferon-inducible enhancer activity of a LINE within the first intron of the IFNAR1 gene (IFNAR1.L1M2a) by knocking out the predicted enhancer using CRISPR, and assessing chro

NIAID Data Ecosystem20

MDA5-binding interferon-inducible RNA sequencing

MDA5-RNA相互作用鉴定

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The goal is to assess whether interferon-inducible RNA regulates type I IFN through cytosolic RNA sensor MDA5. Huh7 cells were treated with or without IFN beta. Anti-MDA5 immunoprecipitation was condu

NIAID Data Ecosystem20

STAT3 Inhibits Autocrine Interferon Signaling in Type I Conventional Dendritic Cells

树突状细胞信号调控

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Type I conventional dendritic cells (cDC1s) are an essential antigen-presenting population, required for generating adaptive immunity against intracellular pathogens and tumors. While the transcriptio

NIAID Data Ecosystem60

IKK-epsilon regulates the balance between the type I and type II interferon responses. Mus musculus

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STAT1ChIP-seq

Virus infection induces the production of type I and type II interferons (IFN-I and IFN-II), cytokines that mediate the antiviral response. IFN-I (IFN-a and -b) induces the assembly of ISGF3 (interfer

NIAID Data Ecosystem20

Modified Stat1 Confers Enhanced Interferon Responsiveness and Improved Baseline Antiviral Host Defense

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