Small Intestinal Goblet Cells Control Humoral Immune Responses and Mobilization During Enteric Infection

NIAID Data Ecosystem2026-05-02 收录

猪肠道免疫学

杯状细胞形态

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https://www.ncbi.nlm.nih.gov/sra/SRP487176 数据链接链接失效反馈

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Goblet cells specific deletion effects intestinal plasma cell composition.

创建时间：

2025-02-01

B cell residency but not T cell-independent IgA switching in the gut requires innate lymphoid cells

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B细胞驻留机制

Immunoglobulin A (IgA)-producing plasma cells derived from conventional B cells in the gut play an important role in maintaining the homeostasis of gut flora. Both T cell-dependent and T cell-independ

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Concentration of IgA measured in fecal samples.

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Escherichia coli is a commensal of the intestine of most mammals, but also an important human pathogen. Within a healthy human its population structure is highly dynamic, where typically a dominant E.

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OTUD3 prevents ulcerative colitis by modulating microbiota-mediated STING activation

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结肠炎机制

Human intestinal Thy1+ mesenchymal cells are considered as heterogeneous population. We performed single cell RNA sequencing (scRNA-seq) to characterize fibroblast populations in the colonic mucosa.Li

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Tissue adaptation is the dominant driver of the proteomic landscape of intestinal intraepithelial lymphocytes

猪肠道免疫学

细胞蛋白质组学

Intestinal intraepithelial T lymphocytes (T-IEL) patrol the single layer of epithelial cells lining the gut, and consist of both induced T-IEL, derived from systemic antigen-experienced lymphocytes, a

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Gender and strain dependent differences in intestinal immunology correlate with differences in microbiota composition (ileum). Mus musculus

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A dysbiosis in the intestinal microbiome plays a role in the pathogenesis of several immunological diseases. These diseases often show a gender bias, suggesting gender differences in immune responses

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Small Intestinal Goblet Cells Control Humoral Immune Responses and Mobilization During Enteric Infection

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