Preterm children are at increased risk of insulin resistance, obesity, and cardiovascular disease. We hypothesise that adverse early life events in preterm children may lead to alterations in the gut
BackgroundMacrophage-derived factors contribute to whole-body insulin resistance, partly by impinging on metabolically active tissues. As proof of principle for this interaction, conditioned medium fr
Data are mean ± SD, median (minimum - maximum values) or %. BMI, body mass index; HOMA-IR, homeostasis model assessment - insulin resistance; Met, metformin; SU, sulfonylureas.aData were analyzed usin
To investigate the mechanisms of lipid-activated protein kinase C (PKC) family, PKCδ or PKCɛ, involved in insulin resistance and fatty acid metabolism, we employed an in vivo adaptation of SILAC to ex
Objective Although previous studies have reported a negative relationship between serum bilirubin concentration and the development of diabetes mellitus (DM), the relationship between bilirubin and in
