Additional file 2 of Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Mice received DivisionRecorder+ or unmodified OT-I T cells and were challenged with LM-OVA. During memory phase we FACS sorted memory CD8+ OT-I T cells (and sub-sorted RFP+ and RFP- cells in the case
Several single-cell transcriptomic approaches have been applied to study immune system in MM, and previously implied “T-cell exhaustion” largely based on comparison with signatures derived in murine c
A healthy pregnancy is associated with dynamic changes in the maternal immune system that facilitates placentation, fetal growth, fetal tolerance, and labor. Pre-pregnancy obesity is associated with s
The goal of this study is to understand the transcriptional features of CD4+ memory T cells induced by CMV seropositivity and explore their TCR repertoire clonality. Overall design: We selected CMV-as