Werner Syndrome (WS) is a human genetic disorder with many features of premature aging. The gene defective in WS (WRN) has been cloned and encodes a protein homologous to several helicases, including
A and B) Colocalization of CERKL (HA) with three markers of SGs (PABP and eIF4E, detected with specific antibodies described in the Materials and Methods section), and the mRNAs poly(A) tail, detected
The first tab shows all proteins from the list of 122_putative mito. proteins for which direct localization exists in the literature (44 proteins), 10 of which were localized to the mitochondrion. The