The fitness unit Darwin (D) is a proxy for the different fitness units used in cell models. Reaction must be orientated in such a way that all fluxes are positive. To define metabolite log-concentrati
Creation of updated CHO Genome-scale metabolic model, iCHO2441 iCHO1766 was obtained from the Bigg models database (King et al., 2016), while iCHO2291 was obtained via the BioModels database (Malik-
shows non-zero minimal/maximal optimization coefficients computed by objective variability analysis (OVA) for each reaction from simulated glucose-limited E. coli fluxes. (XLSX 9 kb)
