Intego-II database March 2025

The Intego-II database builds on three decades of primary care data collection in Flanders, Belgium. Since 1994 pseudonymized electronic medical record (EMR) data from participating general practices are collected within Intego. Its integration with the Belgian Health Data Agency (HDA) provides scalable linkage to mortality, environmental, and disease-specific datasets at the national level. Intego-II incorporates substantial advancements in the database’s structure, operations, and accessibility. A robust two-step Extract-Transform-Load (ETL) process ensures data security, privacy, tidiness, and quality. To enhance international research interoperability, the database is aligned with the OMOP Common Data Model. Intego-II is organized into three key modules: Patient Information, Medical History, and Clinical Encounters, enabling longitudinal analyses across diverse healthcare domains covering, among others, demographic variables, diagnoses, prescriptions, and laboratory test results. Structured quarterly releases with detailed metadata ensure findability and reusability. Researchers can access the full Intego-II database via a secure research environment provided by the HDA, following submission and approval of a study protocol. The data access process can be found on www.intego.be. See "Related Publication" for a methodological description of the Intego-II database.