KHK Bound to GS-1291269
收藏Protein Data Bank Japan2026-01-14 更新2026-04-19 收录
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KHK Bound to GS-1291269 Descriptor: 3-amino-3-(4-{7,7-difluoro-2-[(2R)-2-(trifluoromethyl)azetidin-1-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl}phenyl)-1lambda~6~-thietane-1,1-dione, Ketohexokinase, beta-D-fructofuranose Authors: Ferrao, R.D. Deposit date: 2025-11-04 Release date: 2026-01-07 Last modified: 2026-01-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: The Discovery of GS-1291269: A Neutral Ketohexokinase (KHK) Inhibitor with an Unusual Thietane Amine Functional Group. J.Med.Chem., 69, 2026
创建时间：
2025-11-04
