m6A2Target

m6A2Target is a comprehensive database for the target gene of writers, erasers and readers (WERs) of m6A modification. It intergrates high confidential targets validated by low-throughput experiments and potential targets with binding evidence indicated by high-throughput sequencing such as CLIP-Seq, RIP-seq and ChIP-seq or inferred from m6A WER perturbation followed by high-throughput sequencing such as RNA-Seq, m6A-Seq and Ribo-Seq.m6A2Target是一款针对m6A修饰的写入因子（writers）、擦除因子（erasers）与读取因子（readers，合称WERs）靶基因的综合性数据库。其整合了经低通量实验验证的高可信度靶标，以及带有CLIP-Seq、RIP-seq、ChIP-seq等高通量测序结合证据，或经m6A WERs扰动后结合RNA-Seq、m6A-Seq、Ribo-Seq等高通量测序数据推导而来的潜在靶标。

搜集汇总

背景与挑战

背景概述

RM2Targetv2.0是一个综合性数据库，专门收集RNA修饰的写入者、擦除者和读取者（WERs）与靶基因之间的关联数据，涵盖18种RNA修饰类型。它整合了通过实验验证、高通量测序结合证据以及WER扰动推断的关联，总计超过440万条，覆盖273个WER、973个细胞系/组织和20种生物。