The envelope glycoprotein (E) is the primary target of serotype-specific (TS) neutralizing antibodies (nAbs) after dengue virus infection (DENV1-4). To identify the primary DENV3 nAB targets in sera,
Dengue virus serotype 2 collected in Puerto Rico in 1994 (PR1940, PR6452 and PR315022), and infection clones generated using the 3'UTR sequence of these isolates (IC6452 and IC315022)