Acute myeloid leukemia doxorubicin-resistant mechanism

NIAID Data Ecosystem2026-05-02 收录

白血病耐药机制

肿瘤药物研发

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP517645 数据链接链接失效反馈

官方服务：

资源简介：

To construct doxorubicin-resistant acute myeloid leukemia cell line and explore the mechanism of drug resistance

创建时间：

2024-07-04

Data_Sheet_1_Acute Myeloid Leukemia Chemo-Resistance Is Mediated by E-selectin Receptor CD162 in Bone Marrow Niches.PDF

白血病耐药机制

肿瘤微环境靶向治疗

The interactions of leukemia cells with the bone marrow (BM) microenvironment is critical for disease progression and resistance to treatment. We have recently found that the vascular adhesion molecul

NIAID Data Ecosystem40

Expression profile of shikonin resistant K562 cell line

白血病耐药机制

抗肿瘤药物作用机制

Expression profile of shikonin resistant K562 cell line

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Novel Triazoloquinoxaline-Based Tubulin Polymerization Inhibitor Induces Necroptosis and Significantly Inhibits Metastatic Melanoma Tumor Growth

肿瘤药物研发

黑色素瘤治疗

Metastatic melanoma is the deadliest form of skin cancer, being responsible for 80% of skin cancer deaths. Small molecule colchicine-binding site inhibitors have previously demonstrated preclinical th

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Discovery of Histone Deacetylase 8‑Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies

靶向蛋白降解

肿瘤药物研发

Histone deacetylase 8 (HDAC8) has emerged as promising therapeutic target for several malignancies. In this study, we developed two series of cereblon (CRBN)-recruiting proteolysis-targeting chimeras

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Loss of Oncogenic Notch1 Contributes to PI3 Kinase Inhibitor Resistance in T Lineage Leukemia

白血病耐药机制

靶向治疗研究

Loss of Oncogenic Notch1 Contributes to PI3 Kinase Inhibitor Resistance in T Lineage Leukemia

ChEBI2014-06-24 更新00