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Aurora-A bound to an inhibitor

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Aurora-A bound to an inhibitor Descriptor: 6-BROMO-7-{4-[(5-METHYLISOXAZOL-3-YL)METHYL]PIPERAZIN-1-YL}-2-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-IMIDAZO[4,5-B]PYRIDINE, SERINE/THREONINE-PROTEIN KINASE 6 Authors: Kosmopoulou, M, Bayliss, R. Deposit date: 2010-02-17 Release date: 2010-07-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate. J. Med. Chem., 53, 2010

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2010-02-17
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