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Enantioselective Organocatalytic Sulfenylation of β‑Naphthols

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NIAID Data Ecosystem2026-03-10 收录
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An enantioselective sulfenylation of β-naphthols has been developed for the first time using a newly synthesized cinchona-derived thiourea as the catalyst and N-(arylthio) succinimide (or phthalimide) as an electrophilic sulfur source. Various enantioenriched naphthalenones with an S-containing all-substituted stereocenter were prepared via a dearomatization strategy under mild reaction conditions.

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2018-04-03
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