Highly Enantioselective 3-Furylation of Ketones Using (3-Furyl)titanium Nucleophile
收藏NIAID Data Ecosystem2026-03-06 收录
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A novel asymmetric 3-furyl addition of (3-furyl)Ti(OiPr)3 to ketones in the presence of 10 mol % (S)-BINOL is reported. The catalytic system works excellently for aromatic ketones, α- or β-halophenones, α,β-unsaturated ketones, and acetylfuran, affording products in high yields with excellent enantioselectivities of up to 97% ee.
创建时间:
2010-01-01



