The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set)

We report the transcriptomic landscape of MAIT cell development by examining thymic immature stage 1 and mature stage 3 MAIT cells from mouse thymus, and thymic immature stage 1, stage 2 mature stage 3 MAIT cells from human thymus using RNAseq. Overall design: We bulk-sorted (100 cell) each MAIT cell subset by flow cytometry and compared the differentially expressed genes (DEGs) between subsets.