Jurkat protein half live - Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

NIAID Data Ecosystem2026-03-10 收录

蛋白质周转率

蛋白质稳态

数据链接：

https://www.omicsdi.org/dataset/pride/PXD008629 数据链接链接失效反馈

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资源简介：

Determine half lives of proteins in Jurkat using a dynamic SILAC labeling

创建时间：

2018-04-06

The Plasmodium falciparum exported J domain proteins fine-tune human and malarial Hsp70s: Pathological exploitation of proteostasis machinery

生物医学研究

蛋白质稳态

This dataset represents the documentation and supporting information for the following published review article submitted to Frontiers in Molecular Biosciences: \"The Plasmodium falciparum exported J

DataONE2023-11-05 更新70

The RNA-binding ubiquitin ligase MKRN1 acts as a sensor for ribosome-associated quality control of poly(A)-translation

核糖体相关质量控制

蛋白质稳态

Human cells have evolved multiple quality control mechanisms to ensure protein homeostasis by detecting aberrant mRNAs and protein products which are condemned for rapid decay. Translating ribosomes t

NIAID Data Ecosystem40

Data_Sheet_1_Synonymous mutations in the phosphoglycerate kinase 1 gene induce an altered response to protein misfolding in Schizosaccharomyces pombe.PDF

蛋白质稳态

密码子使用偏好

BackgroundProteostasis refers to the processes that regulate the biogenesis, folding, trafficking, and degradation of proteins. Any alteration in these processes can lead to cell malfunction. Protein

NIAID Data Ecosystem20

A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells

自噬

蛋白质稳态

Multiple myeloma (MM) is the paradigmatic proteasome inhibitor (PI) responsive cancer, but many patients fail to respond. An attractive target to enhance sensitivity is (macro)autophagy, recently foun

DataCite Commons2020-09-04 更新50

Cytoplasmic NAD+ Synthesis and Ribosomal Protein Mono(ADP-Ribosyl)ation Maintain Proteostasis in Ovarian Cancer

蛋白质稳态

翻译机制

Global protein synthesis is upregulated in cancers, and thus cancer cells are prone to errors in translation, which may lead to protein misfolding and proteotoxic stress. The pathways that maintain p

NIAID Data Ecosystem30

Jurkat protein half live - Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

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