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CRISPR/Cas9 mediated Pre-miR-629 gene editing inhibits ELK1 transcription factor and suppresses oncogenic activities in triple negative breast cancer cells

NIAID Data Ecosystem2026-05-02 收录

CRISPRi基因编辑

三阴性乳腺癌治疗

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1221276 数据链接链接失效反馈

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资源简介：

research article

应用场景：

创建时间：

2025-02-08

三阴性乳腺癌治疗

MAPK信号通路

Cytochalasin D, a potent fungal metabolite, has garnered considerable attention due to its diverse biological activities and potential pharmacological applications. Renowned for its ability to disrupt

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List of approved drugs repurposed against TNBC.

药物重定向

三阴性乳腺癌治疗

Triple-negative breast cancer (TNBC) is an aggressive malignancy that requires effective targeted drug therapy. In this study, we employed in silico methods to evaluate the efficacy of seven approved

Figshare2023-08-14 更新20

CRISPR RNA-seq from HepG2 (ENCSR298AQX)

CRISPRi基因编辑

转录组分析

RNA-seq on HepG2 cells treated with a CRISPR gRNA against CHTOP. (CHTOP-BGHcLV22) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/R

NIAID Data Ecosystem20

CRISPR-Cas9 Engineering in Primary Cell Protocol

CRISPRi基因编辑

冠状病毒宿主因子

Ex vivo genome editing of primary human T cells can be used to identify viral host factors

NIAID Data Ecosystem40

File S2.zip

CRISPRi基因编辑

基因敲入序列分析

Annotated sequence files in .ape format (comparable with Genbank) of knock-ins generated by CRISPR/Cas9-mediated genome editing. Unmodified genomic sequence is also provided.

Figshare2023-03-14 更新20

CRISPR/Cas9 mediated Pre-miR-629 gene editing inhibits ELK1 transcription factor and suppresses oncogenic activities in triple negative breast cancer cells

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