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Directly converted 3D brain organoids from APOE4 and APOE3

NIAID Data Ecosystem2026-05-02 收录

阿尔茨海默病模型

脑类器官技术

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP517431 数据链接链接失效反馈

官方服务：

资源简介：

Modeling APOE4 Sporadic Alzheimer in Directly Converted 3D Brain Organoids

应用场景：

创建时间：

2025-07-02

基因剂量调控

阿尔茨海默病模型

The dysregulation of gene dosage due to duplication or haploinsufficiency is a major cause of autosomal dominant diseases such as Alzheimer’s disease. However, there is no rapid and efficient method f

NIAID Data Ecosystem40

Production of AD transgenic piglets.

阿尔茨海默病模型

转基因猪制备

Production of AD transgenic piglets.

Figshare2017-06-07 更新30

APP/PS1 mice characterization and time progression.

阿尔茨海默病模型

神经退行性疾病表征

APP/PS1 mice characterization and time progression.

ChEBI2014-04-30 更新10

Additional file 7 of Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer’s mouse models

阿尔茨海默病模型

微生物组

Additional file 7: Table S2. PERMANOVA results for main figures.

Figshare2024-08-16 更新40

Source data for "Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer’s disease phenotypes in mouse models "

阿尔茨海默病模型

神经炎症适配体治疗

Source data including unprocessed western blot and gels, microscope images and statistical source data for "Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer’s disease phenotypes

NIAID Data Ecosystem20

Directly converted 3D brain organoids from APOE4 and APOE3

资源简介：

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