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On-target and Off-Target of mutant mice among different generations.

Figshare2025-12-03 更新2026-04-28 收录

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https://figshare.com/articles/dataset/On-target_and_Off-Target_of_mutant_mice_among_different_generations_/30779557 数据链接链接失效反馈

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On-target and Off-Target of mutant mice among different generations.

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创建时间：

2025-12-03

CRISPR-Cas9基因编辑

小鼠遗传模型分析

Table S1. The guide RNA and singlestranded Oligonucleotide DNA sequences, their concentrations and the length of genomic regions floxed (in bp) reportedÂ in this study. (XLSX 29 kb)

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miRNA high throughput sequence analysis of AKXD recombinant inbred panel mammary tumors

癌症miRNA表达谱

小鼠遗传模型分析

miRNA sequencing of mammary tumor RNA from 18 [AKXD subline(n) x PyMT]F1. The PyMT strain was FVB/N-TgN(MMTV-PyVT)634Mul. Overall design: Mammary tumor total small RNA from mice representing each of t

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Additional file 2 of Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice

颅面形态测量

小鼠遗传模型分析

Additional file 2: Fig S2. 3D wireframe plot on one Wnt1-Cre transgenic mouse, showing the strongly differing features in grey lines (over2% mean difference and P<0.01), comparing with their Cre-ne

Figshare2024-02-07 更新40

Engineering a miniaturized SaCas9 adenine base editor with reduced RNA off-targets and increased on-target DNA editing efficiencies. Protein domain-altered adenine base editors

腺嘌呤碱基编辑

基因编辑精准度

We compared the editing profile of circularly permuted and domain inlaid Cas9 base editors, and found that on-target editing can be largely maintained following their intradomain insertion, but that s

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On targeting specificity of Cas12b nucleases

基因编辑精准度

CRISPR系统

On targeting specificity of Cas12b nucleases

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