The polycomb proteins BMI-1 and EZH2 are highly overexpressed by Ewing sarcoma (ES), a tumor of stem cell origin that is driven by EWS-ETS fusion oncogenes, most commonly EWS-FLI1. In the current stud

DataCite Commons2020-09-04 更新60

Additional file 2 of Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis

尤文肉瘤

组蛋白去乙酰化酶

Additional file 2: Fig. S1 a, Expression levels of different class I HDAC genes in different pediatric small-round-blue-cell tumors, carcinomas and normal tissues by box plot presentation using a comp

DataCite Commons2022-01-04 更新80

Single cell RNA-seq analysis for normal lymphocytes and IRF4-driven zebrafish tumors

斑马鱼肿瘤模型

单细胞转录组学

Single cell RNA-seq analysis was carried out for 1 normal sample from a control zebrafish line (lck-mCherry) and 5 non-tumor and 14 tumor samples from the IRF4 transgenic line (lck-IRF4). Tumor cells

NIAID Data Ecosystem70

The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes Ewing's-type tumors in zebrafish

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