Tabula Muris Senis是一个全面的小鼠衰老细胞图谱数据库，收录了从小鼠整个生命周期中不同器官的单细胞和批量RNA测序数据。该数据库提供了细胞类型特异性的分子和表型特征，用于研究哺乳动物在生命周期内经历的细胞生物学变化。项目包含20个器官的单细胞转录组分析，是理解基因在细胞类型特异性使用方式及其随时间变化的重要资源。
We identified a homozygous missense alteration (c.75C>A, p.D25E) in CLCC1, encoding a presumptive intracellular chloride channel highly expressed in the retina, associated with autosomal recessive ret
The libraries contained in this experiment come from embryonic day 14 (E.14) liver tissue from mixed sex littermates in mouse strain C57BL/6J. They are stranded PE101 Illumina Hi-Seq RNA-Seq libraries
A goal of a collaboration between the CHDI Foundation and Prof. Jenny Morton at Cambridge University was to identify genes in mice with diurnal/circadian expression patterns. Tissues from wild type mi
Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains
