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Sulfoxide-Directed Enantioselective Synthesis of Functionalized Tetrahydropyridines

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NIAID Data Ecosystem2026-03-07 收录
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The highly selective base-promoted cyclization of enantiopure sulfinyl dienamines provides stereodefined sulfinyl 1,2,3,6-tetrahydropyridines (dr up to 99:1). Subsequent sigmatropic rearrangement affords tetrahydropyridin-3-ols in good yields and selectivities.

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2016-02-18
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