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Transcriptional profiling of CD4+ T cells treated with IFN-beta

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NIAID Data Ecosystem2026-03-14 收录
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Type I interferon upregulates proteins that inhibit HIV replication within infected cells. Here, we characterize IFN-induced gene expression in HIV target cells, primary CD4+ T cells, isolated from several whole blood donors. Cells were collected 0, 3, 6, 12, and 24 hours after treatment with 1000 U/mL IFN-beta and transcriptional changes were evaluated by bulk RNA-seq.

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2023-01-07
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