Crystal structure of cpd 15 bound to Keap1 Kelch domain
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Crystal structure of cpd 15 bound to Keap1 Kelch domain Descriptor: 2-({5-[(2,4-dimethylphenyl)sulfonyl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide, Kelch-like ECH-associated protein 1, PHOSPHATE ION Authors: Silvian, L, Marcotte, D. Deposit date: 2013-01-03 Release date: 2013-05-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg.Med.Chem., 21, 2013
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2013-01-03
