Transcriptional networks governing cardiac precursor cell (CPC) specification are incompletely understood due in part to limitations in distinguishing CPCs from non-cardiac mesoderm in early gastrulat

NIAID Data Ecosystem30

Comparison of brown adipose tissue (BAT) gene expression between Letmd1 KO and wild-type control mice housed at 30C or 7C for 3 weeks.

棕色脂肪组织产热调节

基因敲除转录组

We identified Letm1 domain containing 1 (Letmd1) as a candidate regulator of BAT thermogenesis. We generated Letmd1 KO mice, raised at thermoneutral or cold conditions, and performed RNA-sequencing in

Alliance of Genome Resources20

Role of GADD45 proteins in embryonic stem cells and their derivatives. Mus musculus

干细胞功能基因组学

基因敲除转录组

We generated Gadd45a,b,g triple-knockout mouse embryonic stem cells and performed RNA-seq expression profiling under six different conditions of cell culture and in vitro differentiation. Overall desi

NIAID Data Ecosystem60

Differentially expressed genes in Gdown1 knockout and Gdown1/p53 double-knockout mouse liver [RNA-seq]

基因敲除转录组

器官基因功能研究

To investigate the biological role of Gdown1, differentially expressed genes in Gdown1 knockout and p53/Gdown1 double-knockout mouse liver were analyzed by RNA-seq. Overall design: To investigate diff

NIAID Data Ecosystem30

sn-RNAseq of cells from wide-type embryonic hearts and Emp2-/- ones

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