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Hes6 drives a network with therapeutic potential in castrate-resistant prostate cancer

ChEBI2014-04-17 更新2026-07-21 收录

前列腺癌分子机制

癌症靶向治疗

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36526 数据链接链接失效反馈

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资源简介：

Hes6 drives a network with therapeutic potential in castrate-resistant prostate cancer

应用场景：

创建时间：

2014-04-17

癌症靶向治疗

RAS信号通路抑制

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

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Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

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S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain

蛋白质相互作用

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Ca2+-binding human S100A1 protein is a type of S100 protein. S100A1 is a significant mediator during inflammation when Ca2+ binds to its EF-hand motifs. Receptors for advanced glycation end products (

Figshare2018-02-15 更新10

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

前列腺癌分子机制

激素受体功能

Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants

NIAID Data Ecosystem60

Development of Aptamer-DNAzyme Based Metal-Nucleic Acid Frameworks for Gastric Cancer therapy

核酸适配体药物递送

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All data from source data

NIAID Data Ecosystem20