Effect of LIF and IL-6 on gene expression in JEG-3 and HTR-8/SVneo trophoblastic cells

ChEBI2012-05-31 更新2026-07-21 收录

滋养层细胞生物学

细胞因子调控

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Effect of LIF and IL-6 on gene expression in JEG-3 and HTR-8/SVneo trophoblastic cells

创建时间：

2012-05-31

A Systems Biology approach to determine cell-specific gene regulatory effects of genetic associations in multiple sclerosis

多发性硬化症分子机制

细胞因子调控

We have conducted a cell-specific pathway analysis of the latest GWAS in multiple sclerosis (MS); which analyzed a total of 47,351 cases and 68,284 healthy controls and found more than 200 non-MHC gen

DataONE2019-09-17 更新70

Interleukin-6 Deficiency Influences Cytokine Expression in Susceptible BALB Mice Infected with Leishmania major but Does Not Alter the Outcome of Disease

感染免疫学

细胞因子调控

Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (l

PubMed Central50

Inhibition of Phosphoinositide-3-kinase signaling promotes the stem cell state of trophoblast. Inhibition of Phosphoinositide-3-kinase signaling promotes the stem cell state of trophoblast

细胞信号通路

滋养层细胞生物学

We found that PI3K inhibition increased the expression of stem cell markers in trophoblast stem cells (TSCs). To better understand the PI3K inhibited cells, we compared untreated TSCs with cells treat

NIAID Data Ecosystem40

Immunomodulatory activities of peptides IDR-HH2, IDR-1002 and IDR 1018 in human peripheral blood mononuclear cells (PBMC).

免疫调节肽

细胞因子调控

Cells were stimulated with 20 µg/ml of peptide. 1Experiments were performed 2–4 times and means are presented. All values for peptide treated cells represent significant induction relative to the untr

NIAID Data Ecosystem60

Dysregulation of cytokines in site-specific KD microarray relating to IL-13, IL-37 and IL-17.

川崎病免疫机制

细胞因子调控

All have p-value < 0.05. See Fig 6 for relationships.

NIAID Data Ecosystem40