Co-crystal structure of BTK kinase domain with inhibitor
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Co-crystal structure of BTK kinase domain with inhibitor Descriptor: (7~{S})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, 1,2-ETHANEDIOL, Tyrosine-protein kinase BTK Authors: Zhou, X. Deposit date: 2022-07-01 Release date: 2023-05-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases. J.Med.Chem., 66, 2023
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2022-07-01
