Transcriptional changes induced by ADH5 knocking out in HeLa cells.. Transcriptional changes induced by ADH5 knocking out in HeLa cells.
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ADH5 encodes for the protein GSNOR, an alchol dehydrogenase acting as a denitrosylase. GSNOR reduces S-nitrosoglutathione (GSNO) to an unstable intermediate, S-hydroxylaminoglutathione, which then rearranges to form glutathione sulfonamide, or in the presence of GSH, forms oxidized glutathione (GSSG) and hydroxylamine Overall design: Four biological replicates were analyzed for each of the 2 genotypes
创建时间：
2022-08-12
