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Catalytic, Enantioselective Synthesis of Allenyl Boronates

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NIAID Data Ecosystem2026-03-10 收录
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A method to achieve enantioselective 1,4-hydroboration of terminal and internal enynes to access allenyl boronates under CuH catalysis is described. The reaction typically proceeds in a highly stereoselective manner and tolerates an array of synthetically useful functional groups. The utility of the enantioenriched allenyl boronate products is demonstrated through several representative downstream derivatizations.

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2018-03-28
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