Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine inhibitor 3a
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Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine inhibitor 3a Descriptor: 6-[4-[[2,3-bis(chloranyl)phenyl]sulfonylamino]phenyl]-~{N}-[(3~{R})-pyrrolidin-3-yl]-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide, GLYCEROL, Serine/threonine-protein kinase Sgk1 Authors: Dreyer, M.K, Halland, N, Nazare, M. Deposit date: 2021-09-29 Release date: 2021-12-01 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.506 Å) Cite: Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J.Med.Chem., 65, 2022
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2021-09-29
